Which host factors increase the risk for Helicobacter pylori (Hp) infection?

Updated: Nov 16, 2018
  • Author: Mutaz I Sultan, MBChB, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Host factors may play a role in the acquisition of H pylori infection.

  • Children may be better able to clear acute infection than adults (2% per year).

  • Hypochlorhydria may be necessary to allow H pylori to colonize in the stomach.

  • Normal gastric epithelial cells that line the stomach are necessary for H pylori persistence. H pylori is not found in atrophied metaplastic epithelium.


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