What is the role of bacterial factors in the etiology of Helicobacter pylori (Hp) infection?

Updated: Nov 16, 2018
  • Author: Mutaz I Sultan, MBChB, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Bacterial factors may play a role in the clinical manifestations of H pylori infection.

  • Patients with H pylori infection have 2 basic phenotypes based on the presence or absence of a vacuolating cytotoxin.

  • People with cytotoxin-positive infection have endoscopically proven inflammation that is more pronounced than those of patients with cytotoxin-negative H pylori infection.


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