Which age groups have the highest prevalence of Helicobacter pylori (Hp) infection?

Updated: Nov 16, 2018
  • Author: Mutaz I Sultan, MBChB, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

In developed countries, less than 10% of children younger than 12 years are infected; however, seropositivity increases with age at a rate of 0.3-1% per year. Studies of seropositivity in adults in developed countries revealed prevalences of 30-50%. In the United States, the estimated prevalence is 20% for people younger than 30 years and 50% for those older than 60 years. In developing countries, the prevalence rates are much higher. The serological prevalence rates of H pylori were 15% and 46% in Gambian children younger than 20 months and age 40-60 months, respectively. [24]

Muhsen et al examined the age of acquisition of H pylori infection in a prospective study on Israeli Arab children in 2 villages with different socioeconomic statuses. Prevalence was 6% in the high socioeconomic status village and 10% in the low socioeconomic village in the first 6 months of life; at 18 months, it increased to 9.6% and 51.9%, respectively. [25]


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