What is the efficacy of 5-acetylsalicylic acid (5-ASA) in the treatment of pediatric Crohn disease?

Updated: Oct 23, 2018
  • Author: Andrew B Grossman, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Although oral 5-ASA preparations are commonly used, adult meta-analyses suggest that these preparations do not have a clinically important treatment effect on active Crohn disease and are not superior to placebo for the maintenance of remission in Crohn disease. [19] Topical 5-ASA therapy is available in suppository and enema forms for the treatment of distal colitis.


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