What are the symptoms of perforation in pediatric Crohn disease?

Updated: Aug 16, 2021
  • Author: Andrew B Grossman, MD; Chief Editor: Carmen Cuffari, MD  more...
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Frank perforation is one of the most serious complications of Crohn disease. Perforation typically occurs into other segments of bowel, leading to fistulae, or into areas such as the retroperitoneum, resulting in abscess formation. The presenting features of frank perforation are those of classic peritonitis, though these features may be masked by high-dose corticosteroid therapy.

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