Which factors determine the clinical presentation of pediatric Crohn disease?

Updated: Oct 23, 2018
  • Author: Andrew B Grossman, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

The clinical presentation is primarily determined by the location and extent of the patient’s disease. The terminal ileum is involved in 50-70% of children. More than half of these patients also have inflammation in various segments of the colon, usually the ascending colon. Overall, children seem to be more likely than adults to have colonic involvement; approximately 10-20% have isolated colonic disease. Gastric inflammation, duodenal inflammation, or both may be observed in as many as 30-40% of children with Crohn disease.


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