Which medications in the drug class Lubricants are used in the treatment of Pediatric Constipation?

Updated: Dec 14, 2018
  • Author: Stephen M Borowitz, MD; Chief Editor: Carmen Cuffari, MD  more...
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Lubricating agents soften stools and decrease water absorption from the gastrointestinal tract. They may also promote salt and water secretion by the colon.

Mineral oil (Kondremul)

Mineral oil is a nonabsorbable fat that softens stool and decreases water absorption, partly by its metabolism in the colon to hydroxy fatty acids. This agent is largely tasteless and has an oily consistency that is made more palatable if it is cold or mixed into a fluid (eg, orange juice). When mineral oil is taken in high doses, many children experience seepage of orange oil into their underwear, which can produce perianal pruritus.

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