Which medications in the drug class Stimulant Laxatives are used in the treatment of Pediatric Constipation?

Updated: Dec 14, 2018
  • Author: Stephen M Borowitz, MD; Chief Editor: Carmen Cuffari, MD  more...
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Answer

Stimulant Laxatives

Stimulant laxatives increase peristaltic activity in the gastrointestinal tract. Most of these agents also stimulate salt and water secretion in the colon.

Senna (Ex-Lax, Senokot, Fletcher's, Little Tummys)

Sennosides are plant alkaloids that stimulate colonic salt and water secretion and promote colonic motility. At higher doses, these agents often produce abdominal cramping. Long-term use in animals has not been associated with any evidence of cathartic colon, tachyphylaxis, or secondary hyperaldosteronism.

Bisacodyl (Dulcolax, Bisco-Lax)

Bisacodyl is a colorless and odorless compound that is very poorly absorbed. This agent can be administered orally or rectally. Bisacodyl increases colonic peristalsis and stimulates salt and water secretion.


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