Which medications in the drug class Stool Softeners in Combination With Stimulants are used in the treatment of Pediatric Constipation?

Updated: Dec 14, 2018
  • Author: Stephen M Borowitz, MD; Chief Editor: Carmen Cuffari, MD  more...
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Stool Softeners in Combination With Stimulants

Emollient stool softeners cause stool to soften. Stimulants increase peristaltic activity in the gastrointestinal tract. Most of both these types of agents also promote salt and water secretion by the colon.

Senna concentrate/docusate (Peri-Colace, Senokot, Dok Plus)

Docusate sodium allows incorporation of water and fat into the stool, causing it to soften. Casanthranol is an anthraquinone stimulant hydrolyzed by colonic bacteria into an active compound. Action is usually produced 8-12 hours after administration of this combination.

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