What are the treatment options for refractory inflammatory bowel disease (IBD)?

Updated: Jan 04, 2019
  • Author: David A Piccoli, MD; Chief Editor: Carmen Cuffari, MD  more...
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Patients with refractory IBD or patients who present in a moderate to severe fashion may need a biologic agent, such as infliximab. [23, 25, 26]  Additionally, studies in adult patients have demonstrated that for moderate-to-severe CD, combination therapy with a biologic plus an immunomodulator may be more effective than using a medication from either class alone. [27]

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