What is the role of blood studies in the workup of colitis?

Updated: Jan 04, 2019
  • Author: David A Piccoli, MD; Chief Editor: Carmen Cuffari, MD  more...
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Blood studies should include a complete blood count (CBC); levels of serum electrolytes, blood urea nitrogen (BUN), creatinine, and C-reactive protein (CRP); and liver function test results (eg, transaminases, total protein, serum albumin, and PT). CRP is elevated in as many as 90% of patients with CD and in more than 50% of those with ulcerative colitis (UC). Thrombocytosis and hypoalbuminemia correlate best with histologic inflammation of the colon in UC. Acute-phase reactants are more likely to be elevated in patients with CD than in those with UC.

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