Which medications in the drug class Cephalosporins are used in the treatment of Pediatric Appendicitis?

Updated: Oct 25, 2018
  • Author: Adam C Alder, MD; Chief Editor: Carmen Cuffari, MD  more...
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Cephalosporins are structurally and pharmacologically related to penicillins. They inhibit bacterial cell wall synthesis resulting in bactericidal activity.

Cefoxitin (Mefoxin)

A second-generation cephalosporin, cefoxitin has activity against some gram-positive organisms, gram-negative organisms (nonpseudomonal species), and anaerobic bacteria. It inhibits bacterial cell wall synthesis during active multiplication by binding 1 or more penicillin-binding proteins.

Cefotetan (Cefotan)

Cefotetan is a second-generation cephalosporin indicated for infections caused by susceptible gram-positive cocci and gram-negative rods.

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