What evidence suggests that perforated and nonperforated appendicitis are different pathologic processes?

Updated: Oct 25, 2018
  • Author: Adam C Alder, MD; Chief Editor: Carmen Cuffari, MD  more...
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Interestingly, non-perforated appendicitis and perforated appendicitis are not linked when the epidemiology of the diseases is explored.  The incidence for these two diagnoses differs over time suggesting that they are potentially unrelated to each other and may represent different pathologic processes. Similarities have been shown to other diseases such as diverticulitis and even hospital admissions for influenza.

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