What is pediatric appendicitis more common in developed countries?

Updated: Oct 25, 2018
  • Author: Adam C Alder, MD; Chief Editor: Carmen Cuffari, MD  more...
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Appendicitis is much more common in developed countries. Although the reason for this discrepancy is unknown, potential risk factors include a diet low in fiber and high in sugar, family history, and infection. Gut flora and exposure to gastrointestinal infections have also been proposed as a hygiene theory of appendicitis. There may also be a role of the genetics of the host and the microbiome of the gut in the development of appendicitis and, possibly, with the risk of perforated appendicitis.

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