How is thyroid storm treated in patients with Graves disease and a contraindication to thionamides?

Updated: Mar 16, 2020
  • Author: Madhusmita Misra, MD, MPH; Chief Editor: Robert P Hoffman, MD  more...
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Patients with Graves disease who need urgent treatment of hyperthyroidism but have absolute contraindications to thioamides may be treated acutely with beta-blockers, iodine preparations, glucocorticoids, and bile acid sequestrants as described. Plasmapheresis is sometimes used as a last resort if other measures are not effective. Subsequently, thyroidectomy may be performed after about 7 days of iodine administration. Iodine reduces the vascularity of the gland and the risk for thyroid storm.

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