Which factors precipitate thyroid storm in thyrotoxicosis?

Updated: Mar 16, 2020
  • Author: Madhusmita Misra, MD, MPH; Chief Editor: Robert P Hoffman, MD  more...
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Thyroid storm is precipitated by the following factors in individuals with thyrotoxicosis:

  • Surgery
  • Anesthesia induction [2]
  • Radioactive iodine (RAI) therapy [3]
  • Drugs (anticholinergic and adrenergic drugs, eg, pseudoephedrine; salicylates; nonsteroidal anti-inflammatory drugs [NSAIDs]; chemotherapy [4]
  • Excessive thyroid hormone (TH) ingestion
  • Withdrawal of or noncompliance with antithyroid medications
  • Direct trauma to the thyroid gland
  • Vigorous palpation of an enlarged thyroid
  • Toxemia of pregnancy and labor in older adolescents; molar pregnancy

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