What are the histologic findings in precocious puberty?

Updated: Nov 30, 2020
  • Author: Paul B Kaplowitz, MD, PhD; Chief Editor: Robert P Hoffman, MD  more...
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If CPP is caused by a tumor in the hypothalamic-pituitary area, the histology of the tumor can be important to the patient's prognosis. Gliomas tend to grow more rapidly than astrocytomas, whereas hamartomas are benign.

Treatment of precocious puberty associated with a hamartoma suppresses gonadotropin production by the pituitary without affecting the hamartoma itself.

For information on different non-CNS tumors associated with precocious puberty, see Precocious Pseudopuberty.

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