What makes differentiating between hypogonadotropic hypogonadism and constitutional delay challenging?

Updated: Apr 03, 2019
  • Author: Maria G Vogiatzi, MD; Chief Editor: George T Griffing, MD  more...
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Answer

Hypergonadotropic hypogonadism indicates a primary gonadal defect (congenital or acquired), while hypogonadotropic hypogonadism suggests a hypothalamic/pituitary process (congenital or acquired). The differential diagnosis between hypogonadotropic hypogonadism and constitutional delay can be challenging because low LH values can be seen in both.


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