What are the CNS causes of hypogonadotropic hypogonadism?

Updated: Apr 03, 2019
  • Author: Maria G Vogiatzi, MD; Chief Editor: George T Griffing, MD  more...
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Answer

See the image below.

Types of idiopathic hypogonadotropic hypogonadism. Types of idiopathic hypogonadotropic hypogonadism.

Causes of hypogonadotropic hypogonadism include the following:

  • Central nervous system (CNS) disorders
    • Tumors
    • Miscellaneous causes involving the pituitary/hypothalamic area
      • Langerhans histiocytosis
      • Postinfectious lesions of the CNS
      • Vascular abnormalities of the CNS
      • Radiation therapy
      • Congenital malformations (especially associated with craniofacial anomalies)
      • Head trauma
      • CNS surgery

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