Which conditions should be included in the differential diagnoses of pediatric hypoglycemia?

Updated: Sep 12, 2019
  • Author: Robert P Hoffman, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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A second area of concern involves children with hypoglycemia due to abuse or Münchausen syndrome by proxy. The possibility of exogenous insulin administration must be considered and, if found, reported to the appropriate authorities.

Conditions to consider in the differential diagnosis of hypoglycemia include the following:

  • Adrenal insufficiency - Primary adrenal disease (Addison disease); ACTH deficiency

  • Growth hormone deficiency

  • Hyperinsulinism - Endogenous (genetic, beta-cell tumor); exogenous insulin administration

  • Medium chain acyl-CoA dehydrogenase deficiencies

  • Sepsis

  • Hyperthyroidism

  • Hypopituitarism

  • Glycogen storage diseases - Types 0, I, IV, V, and VI

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