Which medications in the drug class Somatostatin analogs are used in the treatment of Hyperpituitarism?

Updated: Oct 24, 2016
  • Author: Alicia Diaz-Thomas, MD, MPH; Chief Editor: Robert P Hoffman, MD  more...
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Somatostatin analogs

Analogues of somatostatin are the most effective form of medical therapy for GH excess. They effectively inhibit GH secretion, thus lowering the circulating IGF-I concentration. They may shrink tumor size.

Octreotide (Sandostatin, Sandostatin LAR-Depot)

Forty times more potent than the natural hormone somatostatin in inhibiting GH secretion. Available in an immediate-release dosage form (Sandostatin) or long-acting depot form (Sandostatin LAR).

Lanreotide (Somatuline Depot)

Pasireotide (Signifor, Signifor LAR)

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