Which conditions mimic hyperaldosteronism?

Updated: Oct 19, 2018
  • Author: George P Chrousos, MD, FAAP, MACP, MACE, FRCP(London); Chief Editor: Robert P Hoffman, MD  more...
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Answer

Causes of conditions that mimic aldosterone excess include the following:

  • Congenital adrenal hyperplasia (11β-hydroxylase deficiency and 17α-hydroxlyase deficiency) - Low aldosterone, low PRA, elevated steroid intermediates

  • Primary glucocorticoid resistance - High glucocorticoid secretion unsuppressed by dexamethasone

  • Deoxycorticosterone-secreting tumors - Elevated deoxycorticosterone levels

  • Syndrome of apparent mineralocorticoid excess

  • Liddle syndrome

  • Gain of function mutation of mineralocorticoid receptor [18]

  • Licorice ingestion

  • Carbenoxolone


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