What is the prognosis of reconstructive surgery in children with congenital adrenal hyperplasia (CAH)?

Updated: Oct 06, 2020
  • Author: Thomas A Wilson, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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Answer

A study by Roth et al determined that between 2004 and 2014, 12% of girls in the Pediatric Health Information System database with congenital adrenal hyperplasia were treated with female genital restoration surgery. A vaginal procedure was performed in 92% of those who underwent the surgery, a clitoral procedure in 48%, and a perineal procedure (nonclitoral) in 85%. The initial operation was carried out at a median patient age of 9.9 months. Perioperative surgical complications occurred in 4% of the operative group. [21]

A retrospective study by Dangle et al on feminizing reconstructive surgery in 26 toddlers with congenital adrenal hyperplasia reported that the procedures are typically well tolerated and successful. Although complications were found in seven patients (27%), including dysuria, stitch dehiscence, wound separation, and urinary tract infection, revision surgery was needed in only two individuals (7.7%). The patients were followed up for an average of about 6 years. [22]


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