What is the significance of lipoid deposits in congenital adrenal hyperplasia (CAH)?

Updated: Oct 06, 2020
  • Author: Thomas A Wilson, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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Answer

Lipoid deposits in the adrenal cortical cells characterize lipoid adrenal hyperplasia due to a deficiency of StAR. Lipoid deposits are thought to represent cholesterol esters that have accumulated from the inability of the cell to transport cholesterol into the mitochondria.


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