Which is the role of synthetic corticotropin stimulation testing in the evaluation of congenital adrenal hyperplasia (CAH)?

Updated: Oct 06, 2020
  • Author: Thomas A Wilson, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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Answer

Subtle forms of adrenal hyperplasia (as in nonclassic forms of 21-hydroxylase deficiency and nonclassic 3-beta-hydroxysteroid dehydrogenase deficiency) often require a synthetic corticotropin (Cortrosyn) stimulation test to demonstrate the abnormal accumulation of precursor steroids. Nomograms are available for interpreting the results. [5]


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