What are the Endocrine Society's clinical practice treatment guidelines for congenital adrenal hyperplasia (CAH)?

Updated: Oct 06, 2020
  • Author: Thomas A Wilson, MD; Chief Editor: Sasigarn A Bowden, MD  more...
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Answer

The Endocrine Society's 2010 clinical practice guidelines note the following [7] :

  • Prenatal treatment for CAH should be regarded as experimental

  • Glucocorticoid therapy should be carefully titrated to avoid Cushing syndrome

  • Mineralocorticoid replacement is encouraged; in infants, mineralocorticoid replacement and sodium supplementation are encouraged

  • Use of agents to delay puberty and promote growth are experimental

  • Psychiatric support should be encouraged for patients with adjustment problems

  • Medication should be used judiciously during pregnancy and in symptomatic patients with nonclassical CAH


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