What is the most common cause of acquired primary pediatric adrenal insufficiency (Addison disease)?

Updated: Dec 03, 2020
  • Author: Kimberly Tafuri, DO; Chief Editor: Sasigarn A Bowden, MD  more...
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In developed countries, the most common cause of adrenal insufficiency (Addison disease) is autoimmune destruction of the adrenal cortex. [14] This disorder may occur in isolation or may be part of a polyglandular autoimmune disorder (PGAD).

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