Which medications in the drug class Opiate Receptor Antagonists are used in the treatment of Borderline Personality Disorder?

Updated: Nov 05, 2018
  • Author: Roy H Lubit, MD, PhD; Chief Editor: Caroly Pataki, MD  more...
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Opiate Receptor Antagonists

In small studies and case reports, opiate receptor antagonists have been reported to reduce the duration and intensity of dissociative symptoms in patients with BPD and to decrease self-injurious behavior. Evidence suggests that alterations of the endogenous opiate systems contribute to dissociative symptoms in patients with BPD.

Naltrexone (ReVia, Vivitrol)

Naltrexone is a cyclopropyl derivative of oxymorphone that acts as a competitive antagonist at opioid receptors.

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