How does borderline personality disorder (BPD) affect the prognosis of major depression?

Updated: Nov 05, 2018
  • Author: Roy H Lubit, MD, PhD; Chief Editor: Caroly Pataki, MD  more...
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Skodol et al examined data from 1996 participants in a national survey who initially had a diagnosis of major depression. [27] These participants were then reinterviewed 3 years later to determine the persistence and recurrence of the diagnosis. The study concluded that BPD robustly predicted persistence (a finding supported by subsequent studies). Thus, personality psychopathology, most notably BPD, should be assessed in patients with major depressive disorder and should be considered as part of prognosis and treatment.


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