What is the role of fluoxetine (Prozac) in the treatment of anorexia nervosa?

Updated: Jun 10, 2019
  • Author: Bettina E Bernstein, DO; Chief Editor: Caroly Pataki, MD  more...
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Answer

Psychopharmacologic treatment in anorexia nervosa is generally unhelpful, although fluoxetine (Prozac), a selective serotonin reuptake inhibitor (SSRI), may stabilize recovery in patients who have already attained 85% of their weight. If SSRIs are used, however, patients should be carefully monitored for hypomanic or manic adverse effects.

Evidence-based studies show that pharmacotherapy is more effective when combined with CBT and should not be used alone.


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