Which medications in the drug class Antifungal agents are used in the treatment of Diaper Dermatitis (Diaper Rash)?

Updated: Oct 16, 2020
  • Author: Ruchir Agrawal, MD; Chief Editor: Dirk M Elston, MD  more...
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Answer

Antifungal agents

These agents are indicated for suspected candidiasis or proven candidal infection by potassium hydroxide (KOH) preparation or culture. Commonly used topical antifungal agents are nystatin cream or ointment and econazole nitrate cream.

Nystatin (Mycostatin)

Nystatin is a fungicidal and fungistatic antibiotic obtained from Streptomyces noursei. It is effective against various yeasts and yeastlike fungi. It changes the permeability of fungal cell membranes after binding to cell membrane sterols, causing cellular contents to leak.

Clotrimazole topical (Lotrimin AF)

Clotrimazole topical is effective in cutaneous infections. It interferes with RNA and protein synthesis and metabolism. It disrupts fungal cell wall permeability, causing fungal cell death.

Econazole topical (Ecoza)

Econazole is effective in cutaneous infections. It interferes with RNA and protein synthesis and metabolism. It disrupts fungal cell wall permeability, causing fungal cell death.


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