How effective are oral selective inhibitors of Janus kinase (JAK) for the treatment of pediatric atopic dermatitis (AD)?

Updated: Jun 03, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Answer

Baricitinib, an oral selective inhibitor of Janus kinase (JAK)–1 and JAK-2, which modulates proinflammatory cytokine signaling, appears to be have efficacy and be safe in patients with moderate-to-severe atopic dermatitis when used with topical steroids. [61]


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