What is the role of immune response stimulation in the treatment of molluscum contagiosum?

Updated: Aug 09, 2018
  • Author: Ashish C Bhatia, MD, FAAD, FACMS; Chief Editor: Dirk M Elston, MD  more...
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Answer

Intralesional interferon-alfa [58] and topical injections of streptococcal antigen [59] have been shown to be effective in treating patients with resistant molluscum contagiosum. The high cost of these products limits their use to more extensive or resistant infections. The dosing schedule and length of treatment require further evaluation.

A newer compound, Veregen, is a sinecatechin. Its true mechanism of action is unknown. It is a botanical extract from green tea. The 15% ointment is applied topically 3 times a day. It is FDA approved for topical therapy for external genital warts and perianal warts, but it is used off label for molluscum as well as verruca plana. [60]


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