Which medications in the drug class Topical anesthetics are used in the treatment of Pediatric Aphthous Ulcers?

Updated: Feb 25, 2019
  • Author: Michael C Plewa, MD; Chief Editor: Russell W Steele, MD  more...
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Topical anesthetics

These drugs are used to relieve localized pain.

Benzocaine (Anbesol, Hurricaine Gel, Kank-A, Orabase, Orajel)

PABA derivative ester-type local anesthetic; minimally absorbed. Inhibits neuronal membrane depolarization, blocking nerve impulses. Used to control pain.

Lidocaine (Xylocaine)

Available as gel or viscous PO solution. Decreases permeability of neuronal membranes to sodium ions, inhibiting depolarization and blocking transmission of nerve impulses. Initial treatment of choice for small, sparse ulcers. Does not shorten healing time but may help patient to tolerate eating and drinking. Pain relief may be short, and frequent applications may be necessary.

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