Which medications in the drug class Topical corticosteroid elixirs are used in the treatment of Pediatric Aphthous Ulcers?

Updated: Feb 25, 2019
  • Author: Michael C Plewa, MD; Chief Editor: Russell W Steele, MD  more...
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Answer

Topical corticosteroid elixirs

These drugs decrease inflammation by suppressing migration of PMN leukocytes and reversing capillary permeability. Many factors, including the vehicle, the integrity of the mucosal barrier, the amount of friction from adjacent structures, and the amount of salivation determine the extent of mucocutaneous absorption. This type of corticosteroid delivery is indicated when topical or local steroids are not effective, when the lesions are too numerous for practical application, or when the lesions are too difficult to reach with the cotton applicator.

Dexamethasone elixir (Decadron)

Liquid increases delivery of steroid dose to local area when lesions severe or numerous; typical concentration 0.5 mg/5 mL. Close follow-up required to monitor for candidiasis and other secondary infections and adverse effects.


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