What is the criterion for institution of extracorporeal membrane oxygenation (ECMO) for persistent pulmonary hypertension of the newborn (PPHN)?

Updated: Sep 03, 2019
  • Author: Kate A Tauber, MD; Chief Editor: Howard S Weber, MD, FSCAI  more...
  • Print


One criterion for the institution of ECMO is an elevated oxygenation index (OI) that is consistently 40 or higher.

Veno-veno ECMO support can now be provided using a double-lumen catheter in the internal jugular vein; thus, veno-aterial ECMO and ligation of the right common carotid artery can be avoided.  

Although iNO is an effective selective pulmonary vasodilator, ECMO remains the only therapy that has been proven to be life-saving for PPHN. Therefore, timely transfer to an ECMO center is vital for newborns with severe PPHN.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!