What is the focus of the initial treatment for persistent pulmonary hypertension of the newborn (PPHN)?

Updated: Sep 03, 2019
  • Author: Kate A Tauber, MD; Chief Editor: Howard S Weber, MD, FSCAI  more...
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General management principles for the newborn with persistent pulmonary hypertension (PPHN) includes maintaining a normal body temperature and correction of electrolytes or glucose abnormalities and metabolic acidosis.

The treatment strategy is aimed at maintaining adequate systemic blood pressure, decreasing pulmonary vascular resistance, ensuring oxygen release to tissues, and minimizing barotrauma induced by high levels of inspired oxygen and high ventilator pressure settings.

The care of newborns with PPHN requires meticulous attention to detail. Continuous monitoring of oxygenation, blood pressure, and perfusion is critical.

It is important for all those caring for sick newborns to use minimal stimulation and to minimize the use of invasive procedures, such as suctioning.

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