What causes acute pulmonary vasoconstriction in persistent pulmonary hypertension of the newborn (PPHN)?

Updated: Sep 03, 2019
  • Author: Kate A Tauber, MD; Chief Editor: Howard S Weber, MD, FSCAI  more...
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Answer

Answer

The most commonly encountered scenario in PPHN is acute pulmonary vasoconstriction due to acute perinatal events, such as:

  • Alveolar hypoxia secondary to parenchymal lung disease, such as meconium aspiration syndrome, respiratory distress syndrome, or pneumonia

  • Hypoventilation resulting from asphyxia or other neurologic conditions

  • Hypothermia

  • Hypoglycemia (defined as </li></ul>


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