Which medications in the drug class Angiotensin-converting enzyme (ACE) inhibitors are used in the treatment of Coarctation of the Aorta?

Updated: Nov 20, 2018
  • Author: Syamasundar Rao Patnana, MD; Chief Editor: Stuart Berger, MD  more...
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Answer

Angiotensin-converting enzyme (ACE) inhibitors

These agents reduce afterload and decrease myocardial remodeling that worsens chronic heart failure. May be added if hypertension persists despite beta-blocker therapy and no residual arch obstruction is noted.

Captopril (Capoten)

ACE inhibitors decrease the production of angiotensin II, a potent vasoconstrictor, resulting in peripheral vasodilatation and afterload reduction, improved myocardial performance, and theoretically reduced atrioventricular and semilunar valve insufficiency.

Enalapril (Vasotec)

Competitive ACE inhibitor with prolonged duration of action with oral administration.

Reduces angiotensin II levels, reducing aldosterone secretion.


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