What is the mechanical obstruction theory of coarctation of the aorta (CoA)?

Updated: Nov 20, 2018
  • Author: Syamasundar Rao Patnana, MD; Chief Editor: Stuart Berger, MD  more...
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The mechanical obstruction theory explains the increased blood pressure by postulating that a higher blood pressure is required to maintain flow through the coarcted segment and collateral vessels. The stroke volume, ejected into the limited aortic receptacle, produces a higher pressure proximal to coarctation. However, this theory does not explain the following:

  • The lack of relationship between the degree of elevation of blood pressure and the magnitude of obstruction

  • The increased peripheral vascular resistance distal to the site of obstruction

  • The delayed or lack of reduction of blood pressure immediately following relief of obstruction

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