Which patient groups are at highest risk for anomalous left coronary artery from the pulmonary artery (ALCAPA)?

Updated: Aug 10, 2020
  • Author: Mary C Mancini, MD, PhD, MMM; Chief Editor: Syamasundar Rao Patnana, MD  more...
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Answer

There is no known racial predilection.

The occurrence of ALCAPA is generally similar between males and females, and it is not considered an inheritable congenital cardiac defect.

Approximately 85% of patients present with clinical symptoms of congestive heart failure within the first 1-2 months of life. In unusual cases, the clinical presentation with symptoms of myocardial ischemia may be delayed into early childhood. Though rare, presentation in adults have been reported. [5, 6, 7, 8] Rarely, a patient may stabilize following infarction and present with mitral valve regurgitation later in childhood or even adulthood.


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