What are the complications of surgical ligation for patent ductus arteriosus (PDA)?

Updated: Nov 20, 2018
  • Author: Luke K Kim, MD; Chief Editor: Stuart Berger, MD  more...
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Complications of surgical ligation are mostly related to the left lateral thoracotomy. Surgical morbidity and mortality rates are negligible, and early postoperative complications are associated with other complications of prematurity. However, possible injury to the aorta, pulmonary artery, [28] and other structures should be noted.

The results from a study of 125 premature infants found that while PDA ligation was well tolerated overall, a high risk of neurological disability or death from bronchopulmonary dysplasia at 1 year was noted. Increased mortality at 1 year was also associated with increasing preoperative fractional inspired oxygen (FiO2) and lack of prior treatment with cyclooxygenase inhibitors. [29]

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