What is the prognosis of patent ductus arteriosus (PDA)?

Updated: Nov 20, 2018
  • Author: Luke K Kim, MD; Chief Editor: Stuart Berger, MD  more...
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Answer

The prognosis is generally considered excellent in patients in whom the patent ductus arteriosus (PDA) is the only problem. In premature infants who have other sequelae of prematurity, these sequelae tend to dictate prognosis of patent ductus arteriosus (PDA).

Typically, following patent ductus arteriosus (PDA) closure, patients experience no further symptoms and have no further cardiac sequelae. Premature infants who had a significant patent ductus arteriosus (PDA) are more likely to develop bronchopulmonary dysplasia.

Spontaneous closure in those older than 3 months is rare. In those younger than 3 months, spontaneous closure in premature infants is 72-75%. In addition, 28% of children with patent ductus arteriosus (PDA) who were conservatively treated (with prophylactic ibuprofen) reported a 94% closure rate. This rate compared well with rates reported in literature following medical treatment (80-92%).

In the adult patient, the prognosis is more dependent on the condition of the pulmonary vasculature and the status of the myocardium if congestive cardiomyopathy was present before ductal closure. Patients with minimal or reactive pulmonary hypertension and limited myocardial changes may have a normal life expectancy.


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