Which medications in the drug class Antihistamines, Intranasal are used in the treatment of Pediatric Allergic Rhinitis?

Updated: Jun 04, 2021
  • Author: Jack M Becker, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Antihistamines, Intranasal

These agents are an alternative to oral antihistamines to treat allergic rhinitis. Currently, azelastine and olopatadine are the only agents available in the United States and require a prescription.

Azelastine (Astelin Nasal Spray, Astepro)

An effective antihistamine delivered via the intranasal route. Mechanism is similar to PO antihistamines. Systemic absorption occurs and may cause sedation, headache, and nasal burning.

Olopatadine intranasal (Patanase)

Intranasal antihistamine spray for seasonal allergic rhinitis. Available as 6% intranasal solution (delivers 665 mcg/spray).

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