How is ataxia-telangiectasia (AT) differentiated from Wiskott-Aldrich syndrome?

Updated: Apr 28, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

AT presents with symptoms of eczema and recurrent infections; however, in contrast to Wiskott-Aldrich syndrome, patients with AT have decreased levels of immunoglobulin A (IgA) and, often, immunoglobulin E (IgE), and cerebellar ataxia is an early feature.


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