What is the role of cyclosporine and interferon in the treatment of severe combined immunodeficiency (SCID)?

Updated: Apr 28, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

Specific therapy for dermatitis and eosinophilia in severe combined immunodeficiency is immunosuppression with cyclosporine and possible addition of interferon (IFN)-γ. These modalities have been used to treat Omenn syndrome but theoretically should be effective in treating maternal or transfusion-induced GVHD.


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