Which newborn screening test can be used to identify severe combined immunodeficiency (SCID)?

Updated: Apr 28, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

The newborn screening test for T-cell receptor excision circles (TRECs) has been used to identify infants with T-cell lymphopenia. No TRECs were detected in newborns with SCID. [36]


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