Which medications in the drug class Antihistamines with decongestants, oral are used in the treatment of Mold Allergy?

Updated: Sep 18, 2017
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

Antihistamines with decongestants, oral

Antihistamines are most useful for symptoms of itching, sneezing, tearing, or postnasal drip. Decongestants relieve nasal congestion, reducing symptoms of sniffling. Many are available OTC in various combinations of an antihistamine plus pseudoephedrine.

Pseudoephedrine/loratadine (Claritin-D)

Pseudoephedrine/loratadine is a second-generation long-acting antihistamine/decongestant combination with 120 mg or 240 mg of pseudoephedrine.

Cetirizine/pseudoephedrine (Zyrtec-D)

Cetirizine selectively inhibits histamine H1 receptor sites in blood vessels, the GI tract, and the respiratory tract, which, in turn, inhibits the physiologic effects that histamine normally induces at H1 receptor sites. Once-daily dosing is convenient. Bedtime dosing may be useful if sedation is a problem.

Pseudoephedrine stimulates vasoconstriction by directly activating alpha-adrenergic receptors of the respiratory mucosa. It also induces bronchial relaxation and increases heart rate and contractility by stimulating beta-adrenergic receptors.

Pseudoephedrine/fexofenadine (Allegra-D)

Fexofenadine is a nonsedating second-generation medication with fewer adverse effects than first-generation medications. It competes with histamine for H1 receptors in the GI tract, blood vessels, and respiratory tract, reducing hypersensitivity reactions. It does not sedate.

Pseudoephedrine stimulates vasoconstriction by directly activating alpha-adrenergic receptors of the respiratory mucosa. It also induces bronchial relaxation and increases the heart rate and contractility by stimulating beta-adrenergic receptors.


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