Which medications in the drug class Mast-cell stabilizers are used in the treatment of Mold Allergy?

Updated: Sep 18, 2017
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

Mast-cell stabilizers

These agents prevent mast-cell activation and, thus, degranulation. Degranulation releases mediators (eg, histamine), which causes tissue swelling and chemotactic factors to attract eosinophils to the site. This leads to delayed-phase inflammation. This process is obvious in allergic rhinitis and allergic asthma but may also be involved in other clinical conditions related to mold allergy. Nedocromil may have more anti-inflammatory effect than other agents.

Cromolyn sodium (NasalCrom)

NasalCrom (5.2 mg per spray, nasal solution) is used for mast-cell stabilization in allergic rhinitis. The cromolyn sodium nebulizer solution (20 mg/2 mL, nebulizer solution) is used to prevent asthma.


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