Which medications in the drug class Monoclonal antibodies are used in the treatment of Mold Allergy?

Updated: Sep 18, 2017
  • Author: Shih-Wen Huang, MD; Chief Editor: Harumi Jyonouchi, MD  more...
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Answer

Monoclonal antibodies

These agents bind selectively to human IgE on the surface of mast cells and basophils.

Omalizumab (Xolair)

Omalizumab is a recombinant, DNA-derived, humanized IgG monoclonal antibody that selectively binds to the Fc portion of free IgE and thereby blocks binding to receptors on mast cells and basophils. It reduces mediator release, which promotes an allergic response. It is indicated for moderate-to-severe persistent asthma in patients who react to perennial allergens in whom symptoms are not controlled by inhaled corticosteroids.


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